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  1. Estimation of consumer exposure to chemicals : application of simple models.

    Article - En anglais

    Occupational and consumer exposure only recently has become an issue meriting a more systematic approach.

    This paper offers a method for the estimation of consumer exposure on the basis of limited data sets.

    Following a selection of exposure route(s) of concern, acute, subchronic and chronic exposure scenarios are identified based on the expected exposure frequency and duration.

    Algorithms for the estimation of the external exposure are presented and illustrated by example calculations.

    The external and internal exposure assessment is further integrated into a hazard assessment scheme for consumer products including the determination of no-effect levels for man and the calculation of hazard quotients.

    Mots-clés Pascal : Bien consommation, Toxicité, Facteur risque, Evaluation, Homme, Modélisation, Composé chimique, Biodisponibilité, Inhalation, Voie orale, Voie externe, Consommateur, Dose sans effet

    Mots-clés Pascal anglais : Consumer good, Toxicity, Risk factor, Evaluation, Human, Modeling, Chemical compound, Bioavailability, Inhalation, Oral administration, Topical administration, Consumer, No observed effect level

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0675304

    Code Inist : 002B03A. Création : 199406.