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  1. Population exposure to tri- and tetrachloroethene and cancer risk : two cases of drinking water pollution.

    Article - En anglais

    Concentrations up to 212 mug/l of trichloroethene (TCE) and 180 mug/l of tetrachloroethene (TeCE) were found in the drinking water from two villages in Finland.

    To evaluate a possible exposure, urine samples from 95 and 21 inhabitants in these villages and from two control groups of 45 and 15 volunteers were collected.

    Dichloroacetic acid (DCA) and trichloroacetic acid (TCA), the metabolites of TCE and TeCE, were also analyzed.

    The individuals using contaminated water in one of the villages excreted TCA an average 19 mug/d (<1-110 mug/d) and in the other 7.9 mug/d (<1-50 mug/d), while the controls excreted an average 2.0 mug/d (<1-6.4 mug/d) or 4.0 mug/d (<1-13 mug/d).

    Mots-clés Pascal : Contamination, Eau potable, Finlande, Europe, Surveillance sanitaire, Urine, Surveillance biologique, Liquide biologique, Risque, Tumeur maligne, Leucémie, Toxicité, Carcinogène, Homme, Epidémiologie, Ethène(trichloro), Ethène(tétrachloro), Acétique acide(dichloro), Acétique acide(trichloro)

    Mots-clés Pascal anglais : Contamination, Drinking water, Finland, Europe, Sanitary surveillance, Urine, Biological monitoring, Biological fluid, Risk, Malignant tumor, Leukemia, Toxicity, Carcinogen, Human, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0646992

    Code Inist : 002B03H. Création : 199406.