Composite risk score for Kaposi's sarcoma based on a case-control and longitudinal study in the multicenter AIDS cohort study (MACS) population.
The possibility that an agent in addition to human immunodeficiency virus type 1 may be involved in the etiology of Kaposi's sarcoma in acquired immunodeficiency syndrome (AIDS) patients was investigated between 1984 and 1992 in this nested case-control analysis from the Multicenter AIDS Cohort Study (MACS) of homosexual and bisexual men.
A total of 316 cases of Kaposi's sarcoma were identified and compared with 510 participants with AIDS and no evidence of cancer.
More of the Kaposi's sarcoma cases were from Los Angeles and used a higher number of recreational drugs.
The Kaposi's sarcoma cases were also more active sexually.
There was a dose-response relation between Kaposi's sarcoma and the number of sexual partners, with an odds ratio of 2 between the most and least sexually active subgroups.
Mots-clés Pascal : Kaposi maladie, Hémopathie, Epidémiologie, Immunodéficit acquis syndrome, Virose, Infection, Immunopathologie, Peau pathologie, Hématodermie, Homme, Etiologie, Facteur risque, Modèle, Etude longitudinale, Etude multicentrique, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin
Mots-clés Pascal anglais : Kaposi sarcoma, Hemopathy, Epidemiology, AIDS, Viral disease, Infection, Immunopathology, Skin disease, Cutaneous hematologic disease, Human, Etiology, Risk factor, Models, Follow up study, Multicenter study, United States, North America, America, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0643752
Code Inist : 002B19B. Création : 199406.