A retrospective study was done to determine the incidence of and the risk factors predisposing to clinical venous thromboembolism (VTE) in patients treated for high grade gliomas.
Medical records of 68 consecutive patients diagnosed and treated at Saint Francis Hospital and Medical Center from January 1986 to June 1991 were reviewed.
The follow up was to time of death or at least 6 months (up to December 1991).
All clinically suspected episodes of VTE were confirmed by objective tests.
Sixteen episodes of VTE were detected in 13 patients for an overall episode rate of 23.5%. Administration of chemotherapy (p=0.027, two tailed Fisher exact test) and presence of paresis (p=0.031, two tailed Fisher exact test) were statistically significant risk factors for the development of VTE.
Mots-clés Pascal : Thrombose, Gliome malin, Etude cohorte, Parésie, Veine, Facteur risque, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Veine pathologie, Incidence, Complication, Tumeur maligne, Etude longitudinale, Epidémiologie, Système nerveux pathologie, Trouble neurologique, Trouble moteur, Chimiothérapie, Traitement, Homme, Système nerveux central pathologie
Mots-clés Pascal anglais : Thrombosis, Malignant glioma, Cohort study, Paresis, Vein, Risk factor, Cardiovascular disease, Vascular disease, Venous disease, Incidence, Complication, Malignant tumor, Follow up study, Epidemiology, Nervous system diseases, Neurological disorder, Motor system disorder, Chemotherapy, Treatment, Human, Central nervous system disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0622627
Code Inist : 002B17E. Création : 199406.