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  1. Vaccine therapy for HIV : a historical review of the treatment of infectious diseases by active specific immunization with microbe-derived antigens.

    Article - En anglais

    A review of the history of « vaccine therapy » for infections diseases is presented.

    The concept originated when Auzias-Turenne introduced « syphilitic vaccination » or « syphilization » as a treatment for syphilis in Paris in the mid-1800s; his clinical studies probably influenced Pasteur's successful rabies postexposure vaccine trials.

    Robert Loch in Berlin in the 1890s observed that inoculation of tuberculin into patients with tuberculosis induced an inflammatory response in affected tissues, and advocated « tuberculin therapy ».

    Sir Almroth Wright in London in the early 20th century devised methods to measure changes in serum « opsonizing » activity in response to therapeutic inoculations with microbe-derived vaccines.

    Mots-clés Pascal : Homme, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Immunisation, Antigène, Article synthèse, Vaccination, Syphilis, Tréponématose, Spirochétose, Bactériose, Infection, Tuberculose, Mycobactériose, Lèpre, Leishmaniose, Protozoose, Herpès, Virose

    Mots-clés Pascal anglais : Human, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Immunization, Antigen, Review, Vaccination, Syphilis, Treponematosis, Spirachaetosis, Bacteriosis, Infection, Tuberculosis, Mycobacterial infection, Leprosy, Leishmaniasis, Protozoal disease, Herpes, Viral disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0621925

    Code Inist : 002B30A03A. Création : 199406.