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  1. Comparison of eligible randomized patients with two groups of ineligible patients : can the results of the VA total parenteral nutrition clinical trial be generalized ?

    Article - En anglais

    The recently reported VA Cooperative Study « A Randomized Clinical Trial of Total Parenteral Nutrition (TPN) in Malnourished Surgical Patients » randomized 395 pre-operative patients to TPN treatment or control.

    The study concluded that the use of perioperative TPN should be limited to the most severely malnourished patients.

    The study also followed 233 patients eligible for the study who refused to give informed consent for randomization (Eligible Refusers) as well as 1220 patients who were ineligible because they were not sufficiently malnourished (Index Group).

    Patients in the Index Group were determined to be significantly healthier than those in the two eligible groups of patients.

    Mots-clés Pascal : Extrapolation, Randomisation, Voie parentérale, Sélection, Malade, Essai clinique, Alimentation, Chirurgie, Traitement, Homme, Méthodologie, Malnutrition, Etat nutritionnel

    Mots-clés Pascal anglais : Extrapolation, Randomization, Parenteral administration, Selection, Patient, Clinical trial, Feeding, Surgery, Treatment, Human, Methodology, Malnutrition, Nutritional status

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0611675

    Code Inist : 002B30A08. Création : 199406.