To determine the prevalence of opportunistic viral infections in multiple tissues at postmortems of HIV-infected patients, and to relate these findings to their antemortem clinical course.
A study of viral infections in 16 tissues of HIV-positive postmortem cases, by a combination of histology and cell culture (virus isolation).
Clinical details were abstracted retrospectively from patient records.
Forty-seven consecutive autopsies, performed between 1985 and 1992.
Autopsies were conducted by a single pathologist in a single London teaching hospital.
Opportunistic viral infections were detected in 72% of all cases, comprising cytomegalovirus (CMY, 66%), herpes simplex virus (11%), JC virus (6%) and adenovirus (2%).
Mots-clés Pascal : Immunodéficit acquis syndrome, Virose, Infection, Encéphalite, Diarrhée, Postmortem, Autopsie, Hémopathie, Immunopathologie, Cytomegalovirus, Betaherpesvirinae, Herpesviridae, Virus, Herpesvirus hominis, Alphaherpesvirinae, Prévalence, Epidémiologie, Complication, Appareil digestif pathologie, Intestin pathologie, Médecine légale, Angleterre, Grande Bretagne, Royaume Uni, Europe, Homme, Infection opportuniste
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Encephalitis, Diarrhea, Postmortem, Autopsy, Hemopathy, Immunopathology, Cytomegalovirus, Betaherpesvirinae, Herpesviridae, Virus, Herpesvirus hominis, Alphaherpesvirinae, Prevalence, Epidemiology, Complication, Digestive diseases, Intestinal disease, Legal medicine, England, Great britain, United Kingdom, Europe, Human, Opportunistic infection
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0607568
Code Inist : 002B06D01. Création : 199406.