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  1. The design and analysis of cholera vaccine trials : recent lessons from Bangladesh.

    Article - En anglais

    The recent spread of cholera to Latin America, together with the persistent burden of this disease in Asia and Africa, have stimulated efforts to evaluate new cholera vaccines in field settings.

    Although the standard experimental paradigm for vaccine field trials is well established, the success of these trials will also depend on suitable consideration of the epidemiology of cholera and of cholera vaccination in the settings under study.

    Epidemiological studies done in Bangladesh emphasize the importance of appreciating the poorly predictable, multifocal occurrence of cholera in estimating a probable incidence of cholera for a field trial.

    Mots-clés Pascal : Choléra, Bactériose, Infection, Vaccination, Evaluation, Epidémiologie, Incidence, Homme, Bengla Desh, Asie

    Mots-clés Pascal anglais : Cholera, Bacteriosis, Infection, Vaccination, Evaluation, Epidemiology, Incidence, Human, Bangladesh, Asia

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0601982

    Code Inist : 002B05B02L4. Création : 199406.