A nested case-control study was undertaken in the Maribo County cohort of 27,811 women with negative Pap smears.
Sixty women who later developed invasive cervical cancer constituted the cases, and five matched controls were selected from the cohort for each case.
A total of 633 previous, negative smears for the cases and controls were reviewed independently by two pathologists.
The review showed misclassification to be frequent in these smears collected in the period 1966-82.
Thirty-five smears were considered positive at the review.
The misclassification was differential in respect to the women's later disease status.
The odds ratio for patients compared with controls for having at least one positive smear was 22.12 (95% CI 7.54-64.94).
Mots-clés Pascal : Tumeur maligne, Dépistage, Epidémiologie, Col utérus, Programme sanitaire, Col utérus pathologie, Appareil génital femelle pathologie, Classification, Diagnostic erreur, Danemark, Europe, Test Papanicolaou, Frottis vaginal, Exploration, Anatomopathologie, Etude cohorte, Homme, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Medical screening, Epidemiology, Uterine cervix, Sanitary program, Uterine cervix diseases, Female genital diseases, Classification, Error diagnostic, Denmark, Europe, Papanicolaou smear test, Vaginal smear, Exploration, Pathology, Cohort study, Human, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0596235
Code Inist : 002B20C02. Création : 199406.