Detection of hepatitis C virus markers and hepatitis C virus genomic-RNA after needlestick accidents.
Needlestick accidents are a problem among health care workers.
Using sensitive new assays, we evaluated the prevalence and features of hepatitis C virus (HCV) infection following a needlestick accident.
The clinical outcome and evolution of serum HCV markers were assessed in 90 hospital employees (recipients) who sustained needlestick injuries (selected from 146 episodes) involving 92 patients with clinical non-A, non-B hepatitis (donors).
Of the 92 patient donors, 62 (67%) and 88 (96%) were anti-C100-3 and second-generation antiHCV positive, respectively, at the time of the needlestick accident.
During the follow-up period (>=6 months), acute non-A, non-B hepatitis developed in three of 90 recipients about 1 month after the accident.
Mots-clés Pascal : Virose, Infection, Dépistage, Homme, Marqueur biologique, Accident travail, Aiguille, Agent santé, Virus hépatite C
Mots-clés Pascal anglais : Viral disease, Infection, Medical screening, Human, Biological marker, Occupational accident, Needle, Health worker
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0593688
Code Inist : 002B30B01B. Création : 199406.