A nationwide population-based study of the familial aggregation of type 1 (insulin-dependent) diabetes mellitus in Denmark.
The objective of the present study was to assess the prevalence of familial aggregation of Type 1 (insulin-dependent) diabetes mellitus among Danish families with a diabetic child aged 20 years or less and to compare epidemiological data for familial and sporadic cases.
We attempted to identify all patients with Type 1 diabetes aged 0-19 years in Denmark treated at paediatric departments or at departments of internal medicine.
This comprises more than 98% of all patients with Type 1 diabetes in this age group.
Patients were identified through the local diabetic out-patient registry and asked to complete a questionnaire regarding data on diabetes onset and family history.
Of 1574 probands 1419 agreed to participate (90.2%). Additional cases of Type 1 diabetes were found in 171 families (12.8%).
Mots-clés Pascal : Diabète insulinodépendant, Endocrinopathie, Immunopathologie, Maladie autoimmune, Homme, Danemark, Europe, Epidémiologie, Prévalence, Etude familiale, Caractère génétique
Mots-clés Pascal anglais : Insulin dependent diabetes, Endocrinopathy, Immunopathology, Autoimmune disease, Human, Denmark, Europe, Epidemiology, Prevalence, Family study, Genetic character
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0591216
Code Inist : 002B30A01A. Création : 199406.