Liver enzyme activity was examined in 89 South African paint makers currently exposed to a mixture of organic solvents at fairly low levels.
However, the duration of exposure was substantial for many.
Fifty-eight workers (65%) had at least one enzyme value above the upper reference limit.
Gamma glutamyl transferase (gammaGT) activity was elevated in 46% of the workers and aspartate aminotransferase (ASAT) in 52%. In a comparison between workers with high and low solvent exposure, the gammaGT and ASAT values were higher in the most exposed group (eg, gammaGT mean 108 versus 69 U.l-1, P>0.05).
Mots-clés Pascal : Solvant organique, Epidémiologie, Foie pathologie, Toxicité, Exposition professionnelle, Industrie peinture vernis, Homme, Enzyme, Activité enzymatique, Appareil digestif pathologie, République Sud Africaine, Afrique
Mots-clés Pascal anglais : Organic solvent, Epidemiology, Hepatic disease, Toxicity, Occupational exposure, Paint and varnish industry, Human, Enzyme, Enzymatic activity, Digestive diseases, South Africa, Africa
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0588326
Code Inist : 002B03L04. Création : 199406.