While the excess risk of clinical cardiovascular disease among persons with diabetes mellitus is well established, most autopsy studies have not been able to elucidate reasons for the excess, to assess potential selection bias, or to adjust for other cardiovascular risk factors.
The purpose of this study was to examine the predictive relation between diabetes and autopsy evidence of coronary atherosclerosis and myocardial lesions.
Among 8,006 Japanese-American men examined at baseline in 1965-1968 as part of the Honolulu Heart Program, 7,591 were free of cardiovascular disease, and 1,515 of these men died over a 17-year follow-up period.
Protocol autopsies were performed for 83 diabetic men and 159 nondiabetic men.
Mots-clés Pascal : Diabète, Athérosclérose, Myocarde pathologie, Epidémiologie, Homme, Endocrinopathie, Artère coronaire, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Etude longitudinale, Prospective, Cardiopathie, Autopsie, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Diabetes mellitus, Atherosclerosis, Myocardial disease, Epidemiology, Human, Endocrinopathy, Coronary artery, Cardiovascular disease, Vascular disease, Follow up study, Prospective, Heart disease, Autopsy, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0588245
Code Inist : 002B21E02B. Création : 199406.