Raised levels of factor VII coagulant activity (VIIc) have been reported to increase the incidence of CHD.
Preliminary evidence from observational and experimental studies suggests that dietary fat intake is positively associated with VIIc.
We explored this further in 4,246 men aged 45-69, who were found to be free of major CHD when screened for a primary prevention trial of antithrombotic medication.
All men were asked about their consumption of fatty foods and changes in consumption in the last month.
In the 9% of men who reported avoidance of fatty foods in the month before interview, age adjusted VIIc was 7.8% of standard (95% CI 5.1-10.6%) lower than in the remainder.
Mots-clés Pascal : Cardiopathie coronaire, Matière grasse, Facteur coagulation, Angleterre, Grande Bretagne, Royaume Uni, Europe, Facteur risque, Régime alimentaire enrichi, Appareil circulatoire pathologie, Alimentation, Proconvertine, Coagulant, Activité biologique, Adulte, Homme, Corrélation, Age mûr, Epidémiologie
Mots-clés Pascal anglais : Coronary heart disease, Fat, Coagulation factor, England, Great britain, United Kingdom, Europe, Risk factor, Supplemented diet, Cardiovascular disease, Feeding, Factor VII, Coagulant, Biological activity, Adult, Human, Correlation, Middle age, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0588112
Code Inist : 002B12A03. Création : 199406.