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  1. Amount and duration of alcohol intake as risk factors of symptomatic liver cirrhosis : a case-control study.

    Article - En anglais

    We carried out a hospital based case-control study involving 320 patients with symptomatic liver cirrhosis (LC) and 320 pair-matched control individuals, in order to estimate the dose-response relationship between both the daily amount and the duration of alcohol intake and the risk of LC.

    Lifetime alcohol consumption was measured by a standardized and reproducible questionnaire, and expressed as lifetime daily alcohol intake (LDAI) and duration of alcohol consumption (DAC).

    The odds ratio (OR) for T.C was estimated by the conditional logistic regression.

    It increased from 1.0 for lifetime abstainers to 4.2 for LDAI of 225 g or more.

    Mots-clés Pascal : Cirrhose, Ethanol, Toxicité, Foie, Consommation, Appareil digestif pathologie, Foie pathologie, Temps exposition, Relation dose réponse, Epidémiologie, Homme, Italie, Europe, Etude cas témoin

    Mots-clés Pascal anglais : Cirrhosis, Ethanol, Toxicity, Liver, Consumption, Digestive diseases, Hepatic disease, Exposure time, Dose activity relation, Epidemiology, Human, Italy, Europe, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0574751

    Code Inist : 002B03F. Création : 199406.