We carried out a hospital based case-control study involving 320 patients with symptomatic liver cirrhosis (LC) and 320 pair-matched control individuals, in order to estimate the dose-response relationship between both the daily amount and the duration of alcohol intake and the risk of LC.
Lifetime alcohol consumption was measured by a standardized and reproducible questionnaire, and expressed as lifetime daily alcohol intake (LDAI) and duration of alcohol consumption (DAC).
The odds ratio (OR) for T.C was estimated by the conditional logistic regression.
It increased from 1.0 for lifetime abstainers to 4.2 for LDAI of 225 g or more.
Mots-clés Pascal : Cirrhose, Ethanol, Toxicité, Foie, Consommation, Appareil digestif pathologie, Foie pathologie, Temps exposition, Relation dose réponse, Epidémiologie, Homme, Italie, Europe, Etude cas témoin
Mots-clés Pascal anglais : Cirrhosis, Ethanol, Toxicity, Liver, Consumption, Digestive diseases, Hepatic disease, Exposure time, Dose activity relation, Epidemiology, Human, Italy, Europe, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0574751
Code Inist : 002B03F. Création : 199406.