The activity of a number of detergents and disinfectants against respiratory syncytial virus (RSV) was evaluated in an in vitro assay system.
Equal volumes of RSV and serial 10-fold dilutions of the test agents were mixed at 4oC for 5 minutes.
The RSV titer in each mixture was compared with that of untreated RSV alone.
In 14 experiments with input RSV titers ranging from 2.6x103 to 2x107 plaque-forming units/ ml, a 10-fold dilution of 5.25% sodium hypochlorite (generic bleach) inactivated (>=3-log reduction in titer) the virus.
With lower RSV titers inactivation was also observed at a 100-fold dilution of bleach.
Mots-clés Pascal : Détergent, Virus respiratoire syncytial, Pneumovirus, Paramyxoviridae, Virus, Désinfectant, Hygiène, Hôpital, Inactivation, Cytotoxicité, Etude comparative, In vitro
Mots-clés Pascal anglais : Detergent, Respiratory syncytial virus, Pneumovirus, Paramyxoviridae, Virus, Disinfecting agent, Hygiene, Hospital, Inactivation, Cytotoxicity, Comparative study, In vitro
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0571488
Code Inist : 002B02S03. Création : 199406.