Changes in respiratory symptoms and airway hyperresponsiveness after 27 years in a population-based sample of school children.
We wanted to test the hypothesis that childhood airway hyperresponsiveness, even in the absence of respiratory symptoms, is a risk factor for respiratory disease in adulthood.
In a childhood survey of 1963, three groups of 20 children aged 8-11 yrs, were selected from a population sample: 1) a group with recurrent respiratory symptoms (symptomatic group); 2) a group with no symptoms but a positive family history of atopy; and 3) a control group.
All children completed assessment of symptoms, atopy, lung function, and airway hyperresponsiveness.
At the adulthood survey 27 yrs later, 85% of the original sample were reinvestigated.
Only 10 out of 19 subjects (53%) of the original symptomatic group still had symptoms.
Mots-clés Pascal : Asthme, Symptomatologie, Enfant, Homme, Atopie, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Allergie, Immunopathologie, Adulte, Prévalence, Facteur risque, Etude longitudinale, Epidémiologie
Mots-clés Pascal anglais : Asthma, Symptomatology, Child, Human, Atopy, Respiratory disease, Obstructive pulmonary disease, Allergy, Immunopathology, Adult, Prevalence, Risk factor, Follow up study, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0571365
Code Inist : 002B11B. Création : 199406.