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  1. Immunologic specificity of IgG against trimellityl-human serum albumin in serum samples of workers exposed to trimellitic anhydride.

    Article - En anglais

    The specificity of immunoglobulln G (IgG) against trimellityl-human serum albumin (TM-HSA) in serum samples from 11 workers exposed to trimellitic anhydride (TMA) was characterized in this study.

    Levels of IgG against TM-HSA and HSA-conjugates of other acid anhydrides, phthalic anhydride (PA), maleic anhydride (MA), hexahydrophthalic anhydride (HHPA) and tetrachlorophthalic anhydride (TCPA) were estimated by enzyme-linked immunosorbent assay index.

    Inhibition studies using each of 5 HSA acid anhydride conjugates were performed on all 11 serum samples with IgG against TM-HSA, and on the three serum samples with highest IgG binding to P-HSA and M-HSA.

    Mots-clés Pascal : Exposition professionnelle, Albumine, Spécificité, Anhydride organique, Forme liée, Médecine travail, Anticorps, IgG, Adulte, Homme, Phtalique acide, Test radioallergosorbent, Technique ELISA, Trimellitique anhydride, Benzo[c]furane-5carboxylique acide(1,3-dihydro-1,3-dioxo), Peinture

    Mots-clés Pascal anglais : Occupational exposure, Albumin, Specificity, Organic anhydride, Bound form, Occupational medicine, Antibody, IgG, Adult, Human, Phthalic acid, Radioallergosorbent test, ELISA assay, Paint

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0571341

    Code Inist : 002B03L06. Création : 199406.