Several studies have revealed an excess of malformations in children with certain malignancies.
A few environmental causes have been identified which may damage the foetus and lead to malformation and cancer.
However, most of the numerous recognised cancer/malformation syndromes are genetically determined.
This report describes a case-control study of 555 newly diagnosed children with cancer and 1,110 matched controls, chosen from general practitioner lists (GP controls) and hospital admissions (H controls).
Their parents were interviewed on topics of possible aetiological significance and medical records were checked to confirm reports at interview.
Mots-clés Pascal : Tumeur maligne, Leucémie, Lymphome, Malformation, Association morbide, Incidence, Epidémiologie, Etude familiale, Enfant, Homme, Hémopathie maligne, Lymphoprolifératif syndrome, Maladie congénitale, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Leukemia, Lymphoma, Malformation, Concomitant disease, Incidence, Epidemiology, Family study, Child, Human, Malignant hemopathy, Lymphoproliferative syndrome, Congenital disease, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0569103
Code Inist : 002B04B. Création : 199406.