Although most studies on the effect of vitamin A supplementation have reported reductions in childhood mortality, the effects on morbidity are less clear.
We have carried out two double-blind, randomised, placebo-controlled trials of vitamin A supplementation in adjacent populations in northern Ghana to assess the impact on childhood morbidity and mortality.
The Survival Study included 21 906 children aged 6-90 months in 185 geographical clusters, who were followed for up to 26 months.
The Health Study included 1455 children aged 6-59 months, who were monitored weekly for a year.
Children were randomly assigned either 200 000 IU retinol equivalent (100 000 IU under 12 months) or placebo every 4 months; randomisation was by individual in the Health Study and by cluster in the Survival Study.
Mots-clés Pascal : Rétinol, Vitamine, Chimiothérapie, Traitement, Prévention, Epidémiologie, Admission hopital, Mortalité, Enfant, Homme, Ghana, Afrique
Mots-clés Pascal anglais : Retinol, Vitamin, Chemotherapy, Treatment, Prevention, Epidemiology, Hospital admission, Mortality, Child, Human, Ghana, Africa
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0562402
Code Inist : 002B02N. Création : 199406.