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  1. Serum pituitary and sex steroid hormone levels in the etiology of prostatic cancer : a population-based case-control study.

    Article - En anglais

    The hypothesis that serum concentrations of pituitary hormones, sex steroid hormones, or sex hormone-binding globulin (SHBG) affect the occurrence of prostatic cancer was tested in a consecutive sample of 93 patients with newly diagnosed, untreated cancer and in 98 population controls of similar ages without the disease.

    Cases did not differ significantly from controls regarding serum levels of luteinising hormone (LH) or follicle stimulating hormone (FSH).

    Remarkably close agreement was found for mean values of total testosterone (15.8 nmol l-1 in cases and 16.0 in controls), and free testosterone (0.295 and 0.293 nmol l-1, respectively), with corresponding odds ratios for the highest vs lowest tertile of 1.0 (95% confidence interval 0.5-1.9) for testosterone and 1.2 (95% confidence interval 0.6-2.4) for free testosterone.

    Mots-clés Pascal : Tumeur maligne, Hormone hypophysaire, Epidémiologie, Prostate, Hormone stéroïde sexuelle, Prostate pathologie, Voie urinaire pathologie, Appareil génital mâle pathologie, Sérum, Etiologie, Homme, Etude cas témoin

    Mots-clés Pascal anglais : Malignant tumor, Pituitary hormone, Epidemiology, Prostate, Sex steroid hormone, Prostatic disease, Urinary tract disease, Male genital diseases, Serum, Etiology, Human, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0556114

    Code Inist : 002B14D02. Création : 199406.