When lacking information on confounding variables, epidemiologists have used surrogates which are antecedents of both the exposures and confounders of interest.
The usefulness of this strategy is explored in a series of scenarios for a prospective epidemiologic study wherein risk ratios relating antecedent to confounder, antecedent to exposure, and confounder to exposure were varied.
Antecedent-adjusted, confounder-adjusted, and crude risk ratios were calculated and compared.
The antecedent-adjusted risk ratio was useful, that is, was closer to the confounder-adjusted risk ratio than was the crude risk ratio, in 1,067 (49%) of 2,187 scenarios.
Mots-clés Pascal : Epidémiologie, Méthodologie, Prospective
Mots-clés Pascal anglais : Epidemiology, Methodology, Prospective
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0549341
Code Inist : 002B30A01A1. Création : 199406.