The mortality pattern among 999 Danish patients who had been subjected to angiography of the carotid artery with the alpha-ray emitting X-ray contrast media Thorotrast during the period 1935-47 was assessed by record linkage with the National Death Registry through 1989.
Standardized mortality ratios (SMR) were calculated relative to the general population.
The overall SMR was increased by 18 times during the first 3 years after Thorotrast injection.
This rate reflects the often serious, underlying neurological conditions for which angiography was performed, however, mortality was increased by 3-4 fold even for the follow up period after the first 3 years.
Mots-clés Pascal : Thorium composé, Angiographie, Epidémiologie, Produit contraste, Toxicité, Radiodiagnostic, Exploration, Mortalité, Homme, Thorium dioxyde, Danemark, Europe, Etude cohorte
Mots-clés Pascal anglais : Thorium compound, Angiography, Epidemiology, Contrast media, Toxicity, Radiodiagnosis, Exploration, Mortality, Human, Denmark, Europe, Cohort study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0539220
Code Inist : 002B02U08. Création : 199406.