In an urban area of Guinea-Bissau, 384 children were enrolled in a rondomized trial comparing morbidity and mortality rates after receiving high-titer Edmonston-Zagreb (EZ) measles vaccine administered from 4 months of age, with a control group receiving inactivated poliomyelitis vaccine at 4 months of age and the standard Schwarz vaccine from 9 months of age.
Children were followed to the age of at least 3 years.
The mortality ratio of the EZ vaccinees compared with control subjects was 1.79 (range, 1.06 to 3.02; p=0.027) if children were excluded at the time of migration; if deaths after migration were included, the mortality ratio was 1.53.
(range, 0.94 to 2.49; p=0.087).
Mots-clés Pascal : Rougeole, Virose, Infection, Guinée Bissau, Afrique, Vaccination, Milieu urbain, Efficacité, Programme sanitaire, Enfant, Homme, Sexe, Mortalité, Pronostic, Long terme, Etude statistique, Morbidité
Mots-clés Pascal anglais : Measles, Viral disease, Infection, Guinea-Bissau, Africa, Vaccination, Urban environment, Efficiency, Sanitary program, Child, Human, Sex, Mortality, Prognosis, Long term, Statistical study, Morbidity
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0539045
Code Inist : 002B30A01C. Création : 199406.