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  1. Risk assessment adjusted for gestational age in maternal serum screening for Down's syndrome.

    Article - En anglais


    To investigate the relation between errors in calculation of gestational age and assessment of risk of Down's syndrome and to analyse the implications for screening programmes.

    Design-Retrospective analysis of dating of gestational age by menstrual history upsilon ultrasound scan.

    Computer program with maternal age and concentrations of alpha fetoprotein and free bêta human chorionic gonadotrophin to calculate risk for a range of effected dates of delivery.

    Computer simulated prospective application of new screening programme.

    Setting-Teaching hospitals in Nottingham

    Subjects-31 561 women with singleton pregnancies with gestational age based on routine ultrasound scan.

    Computer simulation of 20 000 women in three age ranges (up to 37; up to 40; all).

    Mots-clés Pascal : Association morbide, Dépistage, Foetus, Homme, Age, Sexe, Femelle, Gestation, Gestation pathologie, Mongolisme

    Mots-clés Pascal anglais : Concomitant disease, Medical screening, Fetus, Human, Age, Sex, Female, Pregnancy, Pregnancy disorders, Down syndrome

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0520990

    Code Inist : 002B30A03B. Création : 199406.