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  1. Occupational dermatitis from isothiazolinones in the nylon production.

    Article - En anglais

    Kathon is a biocide consisting of a mixture of two isothiazolinone derivatives (5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one) in an approximate ratio of 3: 1, respectively, and with MgCl2 and Mg(NO3)2 present as stabilizers.

    The isothiazolinones are marketed under several brand names, and the concentration of the active ingredient varies according to their intended application.

    At a concentration of 3-15 ppm it shows activity against a wide spectrum of fungi, gram-positive and gram-negative bacteria.

    Contact allergy to it has been caused by cosmetics and also by products used in the pottery and various other industries.

    Recently we had the opportunity to observe 6 cases of occupational allergic contact dermatitis from an isothiazolinone mixture named Grotan TK 2 in a large textile industry producing nylon.

    Mots-clés Pascal : Dermatite contact, Industrie textile, Peau pathologie, Immunopathologie, Médecine travail, Allergie, Maladie professionnelle, Amide polymère, Composé chimique, Grotan TK2, Isothiazoline dérivé, Homme

    Mots-clés Pascal anglais : Contact dermatitis, Textile industry, Skin disease, Immunopathology, Occupational medicine, Allergy, Occupational disease, Nylon, Chemical compound, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0498080

    Code Inist : 002B06C04. Création : 199406.