Occupational dermatitis from isothiazolinones in the nylon production.
Kathon is a biocide consisting of a mixture of two isothiazolinone derivatives (5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one) in an approximate ratio of 3: 1, respectively, and with MgCl2 and Mg(NO3)2 present as stabilizers.
The isothiazolinones are marketed under several brand names, and the concentration of the active ingredient varies according to their intended application.
At a concentration of 3-15 ppm it shows activity against a wide spectrum of fungi, gram-positive and gram-negative bacteria.
Contact allergy to it has been caused by cosmetics and also by products used in the pottery and various other industries.
Recently we had the opportunity to observe 6 cases of occupational allergic contact dermatitis from an isothiazolinone mixture named Grotan TK 2 in a large textile industry producing nylon.
Mots-clés Pascal : Dermatite contact, Industrie textile, Peau pathologie, Immunopathologie, Médecine travail, Allergie, Maladie professionnelle, Amide polymère, Composé chimique, Grotan TK2, Isothiazoline dérivé, Homme
Mots-clés Pascal anglais : Contact dermatitis, Textile industry, Skin disease, Immunopathology, Occupational medicine, Allergy, Occupational disease, Nylon, Chemical compound, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0498080
Code Inist : 002B06C04. Création : 199406.