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  1. Assessing the cost effectiveness of adjuvant therapies in early breast cancer using a decision analysis model.

    Article - En anglais


    We have developed a decision analysis model that uses the results of available randomized controlled trials to model the natural history of early breast cancer and assess the potential clinical and financial effects of using adjuvant therapies, Patients and Methods: The original model was used to assess the impact of chemotherapy in hypothetical groups of 45-year-old and 60-year-old node-negative, estrogen receptor-negative women.

    Using the 1992 Early Breast Cancer Trialists' Collaborative Group report, we have expanded and revised the model to assess: 1) the role of tamoxifen alone, chemotherapy alone, or combined therapy in pre-menopausal women, and 2) chemotherapy in elderly women with node-negative, estrogen receptor-negative cancer.

    Mots-clés Pascal : Anticancéreux, Chimiothérapie, Analyse coût efficacité, Glande mammaire, Glande mammaire pathologie, Tumeur maligne, Analyse décision, Homme, Qualité vie, Traitement, Modèle Markov, Femelle, Traitement adjuvant

    Mots-clés Pascal anglais : Antineoplastic agent, Chemotherapy, Cost efficiency analysis, Mammary gland, Mammary gland diseases, Malignant tumor, Decision analysis, Human, Quality of life, Treatment, Markov model, Female, Adjuvant treatment

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0482908

    Code Inist : 002B02R02. Création : 199406.