Does the predictive value of baseline coronary risk factors change over a 30-year follow-up ?
The association of baseline serum total cholesterol, systolic blood pressure, smoking and body mass index with coronary heart disease (CHD) mortality was analyzed among 1,619 men aged 40-59 at baseline.
Analyses were made separately for the first, second and third decade of follow-up.
Serum cholesterol and smoking more than 9 cigarettes daily were strong predictors of risk of CHD death (n=450) occurring early and late during the 30-year follow-up.
After 20 years offollow-up, systolic blood pressure was no longer associated with CHD risk.
In contrast, highest tertile of body mass index (over 24.7 kg/m2) was only then associated with increased CHD risk.
Mots-clés Pascal : Cardiopathie coronaire, Homme, Etude longitudinale, Facteur risque, Variation temporelle, Appareil circulatoire pathologie, Pronostic, Epidémiologie
Mots-clés Pascal anglais : Coronary heart disease, Human, Follow up study, Risk factor, Time variation, Cardiovascular disease, Prognosis, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0479470
Code Inist : 002B12A03. Création : 199406.