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  1. Oral contraceptives and endometrial cancer : do other risk factors modify the association ?

    Article - En anglais

    The joint effect of use of combination-type oral contraceptives and other exposure factors on risk of endometrial cancer was examined in data from a multicenter case-control study conducted in 5 areas of the United States.

    Cases were 405 women with histologically confirmed invasive epithelial endometrial cancer first treated at one of 7 participating hospitals.

    A total of 297 population-based controls of similar age, race, and geographic area were selected as a comparison group.

    Information on exposure factors was derived from in-person interviews.

    Combination-type oral contraceptive (COC) use was associated with a significant reduction in risk of endometrial cancer, with an adjusted odds ratio (OR) of 0.4 (95% confidence interval 0.3 to 0.7) for ever compared to never use.

    Mots-clés Pascal : Tumeur maligne, Contraceptif, Endomètre, Facteur risque, Utérus pathologie, Appareil génital femelle pathologie, Voie orale, Epidémiologie, Homme

    Mots-clés Pascal anglais : Malignant tumor, Contraceptive, Endometrium, Risk factor, Uterine diseases, Female genital diseases, Oral administration, Epidemiology, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0470223

    Code Inist : 002B20C02. Création : 199406.