During 1978-1990, 346 patients with sarcoidosis were enrolled in our institute.
Of 346 patients, 295 patients were eligible for evaluation on the clinical course and prognosis.
According to their clinical presentations, they were classified into 3 groups; severe, moderate and mild sarcoidosis.
Of the 295 patients, 27 (9.2%) were classified as severe sarcoidosis who developed serious illness including involvement of the heart (8), lung (6), muscles (5), eyes (3), central nervous system (CNS) (3) or liver (2).
The mean interval between the onset of disease to severe disability was 58.3 months.
The interval was particularly long in those patients who presented with either pulmonary (100.8 months) or liver sarcoidosis (108 months).
Mots-clés Pascal : Sarcoïdose, Indice gravité, Angiotensin converting enzyme, Enzyme, Japon, Asie, Pronostic, Pathogénie, Maladie système, Homme, Marqueur biologique, Corticostéroïde, Chimiothérapie, Traitement, Facteur risque, Epidémiologie
Mots-clés Pascal anglais : Sarcoidosis, Severity score, Angiotensin converting enzyme, Enzyme, Japan, Asia, Prognosis, Pathogenesis, Systemic disease, Human, Biological marker, Corticosteroid, Chemotherapy, Treatment, Risk factor, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0447418
Code Inist : 002B07. Création : 199406.