Federation of American Societies for Experimental Biology. Annual meeting. Anaheim CA (USA), 1992/04/08.
We studied growth in infected children given one dose (600 mg) or two doses of albendazole per school year.
Children were examined and allocated at random within sex by descending hookworm egg count to one of three groups: placebo (n=93), one dose (1'7, n=96) or two doses (2'7, n=95).
Each child was treated and then re-examined and treated 3.6 and 8.2 mo later (Exams 2 and 3).
The 1'7 and 2'7 groups gained significantly more by Exam 3 than the placebo group in weight (1.1 and 0.9 kg more, respectively), percent weight-for-age (3.3 and 2.7 percentage points more), percent weight-for-height (3.1 and 2.9 percentage points more), percent arm circumference-for-age (2.3 and 2.0 percentage points more) and triceps and subscapular skinfolds but did not differ significantly from each other.
Mots-clés Pascal : Kenya, Afrique, Age scolaire, Enfant, Homme, Albendazole, Voie orale, Traitement, Chimiothérapie, Relation dose réponse, Trichocéphalose, Nématodose, Helminthiase, Infection, Ankylostomiase, Ascaridiase, Prise poids, Croissance, Développement postnatal, Développement staturopondéral, Poids corporel, Antiparasitaire, Anthelminthique
Mots-clés Pascal anglais : Kenya, Africa, School age, Child, Human, Oral administration, Treatment, Chemotherapy, Dose activity relation, Trichuriasis, Nematod disease, Helminthiasis, Infection, Hookworm infection, Ascariasis, Weight gain, Growth, Postnatal development, Somatic growth, Body weight, Parasiticid, Anthelmintic
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0447109
Code Inist : 002B02S06. Création : 199406.