Accurate detection of maternal antibodies to HIV in newborn whole blood dried on filter paper.
The testing of neonatal blood specimens dried on filter paper for maternal HIV antibodies, using an enzyme immunoassay (EIA) with confirmation of repeatedly reactive specimens by immunoblot (IB), was first described in 1987.
It has been used to conduct large, unlinked, anonymous HIV seroprevalence surveys for surveillance of HIV in child-bearing women in several countries.
We directly assessed the sensitivity and specificity of this combination of tests to detect maternal HIV antibodies.
Serum samples obtained from mothers delivering at a major hospital in Kinshasa, Zaire were screened for HIV antibody using the rapid assay HIVCHEK.
Mots-clés Pascal : Immunodéficit acquis syndrome, Virose, Infection, Diagnostic, Sang total, Séropositivité, Prévalence, Hémopathie, Immunopathologie, Maladie sexuellement transmissible, Mère pathologie, Nouveau né, Homme, Séchage, Papier filtre, Méthode immunoenzymatique, Méthode immunoblotting, Exploration, Biologie moléculaire, Epidémiologie
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Diagnosis, Whole blood, Seropositivity, Prevalence, Hemopathy, Immunopathology, Sexually transmitted disease, Maternal diseases, Newborn, Human, Drying, Filter paper, Enzyme immunoassay, Immunoblotting assay, Exploration, Molecular biology, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0445989
Code Inist : 002B06D01. Création : 199406.