Decline of childhood Haemophilus influenzae type b (Hib) disease in the hib vaccine era.
Objective.-Effective Haemophilus influenzae type b (Hib) conjugate vaccines were first licensed for use in US children at least 18 months old in December 1987 and for infants at least 2 months old in October 1990.
We evaluated trends in Hib disease associated with licensure of Hib conjugate vaccines.
Design.-Data from two sources, an intensive laboratory-based active surveillance system and the National Bacterial Meningitis Reporting System (NBMRS), were used separately to evaluate disease incidence.
Data from vaccine manufacturers on Hib vaccine doses distributed in the United States were compared with trends in Hib disease incidence.
Mots-clés Pascal : Infection, Système nerveux pathologie, Prévention, Résultat, Traitement, Enfant, Homme, Etude statistique, Haemophilus influenzae, Pasteurellaceae, Bactérie, Vaccin, Méningite
Mots-clés Pascal anglais : Infection, Nervous system diseases, Prevention, Result, Treatment, Child, Human, Statistical study, Haemophilus influenzae, Pasteurellaceae, Bacteria, Vaccine, Meningitis
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0391676
Code Inist : 002B05B02I. Création : 199406.