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  1. Porpofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients : a cost-benefit analysis.

    Article - En anglais

    The purpose of this study was to evaluate and compare the clinical effects, safety, and economic cost of propofol and midazolam in the sedation of patients undergoing mechanical ventilation in the ICU.

    Eighty-eight critically ill patients were studied and randomly allocated to receive short-term (less than 24 h), medium-term (24 h to 7 days), and prolonged (more than 7 days) continuous sedation with propofol (n=46) or midazolam (n=42).

    Mean doses required were 2.36 mg/kg/h for propofol and 0.17 mg/kg/h for midazolam.

    Mots-clés Pascal : Appareil respiratoire pathologie, Réanimation respiratoire, Réanimation, Economie santé, Homme, Traitement, Etude comparative, Fonction respiratoire, Chimiothérapie, Ventilation artificielle, Sédatif, Midazolam, Propofol

    Mots-clés Pascal anglais : Respiratory disease, Respiratory intensive care, Resuscitation, Health economy, Human, Treatment, Comparative study, Lung function, Chemotherapy, Artificial ventilation, Sedative

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0372214

    Code Inist : 002B27B02. Création : 199406.