Cigarette smoking and the risk of endometrial cancer.
A case-control study involving 405 cases of epithelial endometrial carcinoma (newly diagnosed between 1987 and 1990 in five US areas) and 297 population controls enabled evaluation of risk in relation to detailed smoking characteristics.
Cigarette smokers were at a reduced risk of disease, with the effect primarily restricted to women whose diseases were detected postmenopausally (relative risk (RR)=0.6, 95% confidence interval 0.4-0.9).
Among postmenopausal women, current smokers showed the greatest reduction in risk (RR=0.4, 95% confidence interval 0.2-0.7), with former smokers, including those who had recently stopped, being less affected (RR=0.8).
Mots-clés Pascal : Tabagisme, Endomètre, Femme, Homme, Toxicité, Tumeur maligne, Utérus pathologie, Appareil génital femelle pathologie, Epidémiologie, Postménopause, Traitement substitutif, Oestrogène, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin
Mots-clés Pascal anglais : Tobacco smoking, Endometrium, Woman, Human, Toxicity, Malignant tumor, Uterine diseases, Female genital diseases, Epidemiology, Postmenopause, Replacement therapy, Estrogen, United States, North America, America, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0343023
Code Inist : 002B03E. Création : 199406.