The purpose of this study was to prospectively examine the relation of dehydroepiandrosterone sulfate (DHEAS) to bone mineral density in a community-based sample of 260 men and 162 women who were residents of Rancho Bernardo, California.
DHEAS levels had been measured in plasma obtained in 1972-1974 when the men were 50-74 years of age and the women were 55-74.
In 1988-1991, bone mineral density was measured at the lumbar spine and hip using dual x-ray absorptiometry, and at the mid-radius and ultradistal radius using single photon absorptiometry.
Among men, there was a significant decrease in DHEAS levels and bone mineral density at the hip, ultradistal radius, and midshaft radius with increasing age.
Mots-clés Pascal : Déhydroépiandrostérone sulfate, Densité, Epidémiologie, Ostéoporose, Androgène, Hormone stéroïde sexuelle, Os, Californie, Etats Unis, Amérique du Nord, Amérique, Vieillard, Homme, Sexe, Système ostéoarticulaire pathologie, Ostéopathie, Prospective, Marqueur biologique
Mots-clés Pascal anglais : Dehydroepiandrosterone sulfate, Relative density, Epidemiology, Osteoporosis, Androgen, Sex steroid hormone, Bone, California, United States, North America, America, Elderly, Human, Sex, Diseases of the osteoarticular system, Bone disease, Prospective, Biological marker
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0339670
Code Inist : 002B15A. Création : 199406.