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  1. Meta-analysis of the literature or of individual patient data : is there a difference ?

    Article - En anglais

    The use of meta-analyses or overviews to combine formally the results of related randomised clinical trials is becoming increasingly common.

    However the distinction between analyses based on information extracted from the published literature and those based on collecting and reanalysing updated individual patient data is not clear.

    We have investigated the difference between meta-analysis of the literature (MAL) and meta - analysis of individual patient data (MAP) by comparing the two approaches using randomised trials of cisplatin-based therapy in ovarian cancer.

    The MAL was based on 788 patients and the MAP on 1329 and estimated median follow-ups were 3.5 and 6.5 years, respectively.

    Mots-clés Pascal : Homme, Etude comparative, Evaluation performance, Littérature scientifique, Individu, Donnée, Métaanalyse

    Mots-clés Pascal anglais : Human, Comparative study, Performance evaluation, Scientific literature, Individual, Data, Metaanalysis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0334148

    Code Inist : 002B30A11. Création : 199406.