Observational epidemiologic studies suggest that the incidence of cardiovascular disease is reduced by about 50% in users of unopposed estrogens, but the reduction may have been overestimated because of a greater tendency for women at lower risk to use estrogens.
To minimize bias due to such behavior, the authors conducted a case-control study of first myocardial infarction among Massachusetts women aged 45-69 years during 1986-1990, in which each of 858 cases was age-matched with a control from the same geographic area, and important correlates of estrogen use and myocardial infarction were controlled by conditional logistic regression.
Mots-clés Pascal : Infarctus, Appareil circulatoire pathologie, Hormone, Myocarde, Cardiopathie coronaire, Epidémiologie, Femme, Homme, Oestrogène, Traitement substitutif, Massachusetts, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin
Mots-clés Pascal anglais : Infarct, Cardiovascular disease, Hormone, Myocardium, Coronary heart disease, Epidemiology, Woman, Human, Estrogen, Replacement therapy, Massachusetts, United States, North America, America, Case control study
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0303838
Code Inist : 002B12A03. Création : 199406.