Incidence of respiratory cancer among workers exposed to chloromethyl-ethers.
A factory in France had used technical-grade chloromethyl-methyl-ether in the manufacture of anion exchange resins since 1958.
Technical-grade chloromethyl-methyl-ether contains a human lung carcinogen, bis-chloromethyl-ether.
The purpose of this cohort study was to determine if workers at the factory whose jobs had involved potential exposure to technical chloromethyl-methyl-ether had a higher incidence of lung cancer than coworkers, or others without potential exposure.
Lung cancer occurred at a higher rate among potentially exposed workers than among nonexposed workers at the same plant (rate ratio (RR)=5.0, 95% confidence interval (Cl) 2.0-12.3), or among an external reference population (RR=7.6, 95% Cl 4.3-13.5).
Mots-clés Pascal : Tumeur maligne, Exposition professionnelle, Epidémiologie, Bronchopulmonaire, Appareil respiratoire pathologie, Homme, Toxicité, France, Europe, Incidence, Ether(chloromethyl), Carcinogène, Etude cohorte
Mots-clés Pascal anglais : Malignant tumor, Occupational exposure, Epidemiology, Bronchopulmonary, Respiratory disease, Human, Toxicity, France, Europe, Incidence, Carcinogen, Cohort study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0303835
Code Inist : 002B11A. Création : 199406.