Methodological considerations in case-control studies to evaluate BCG vaccine effectiveness.
Several case-control studies evaluating the effectiveness of BCG vaccine in the last decade have presented contradictory results like previous prospective studies.
Methodological differences could explain some of the case-control study results.
This study explores the possibility that contradictory results could be imputed to the choice of different series of controls.
Three controls were compared for each case of tuberculous meningitis: neighbourhood, hospital and household.
BCG effectiveness estimates were 86.8%, 92.0% and 29.5%, respectively.
Mots-clés Pascal : Vaccin, Epidémiologie, BCG, Efficacité, Méthodologie, Brésil, Amérique du Sud, Amérique, Immunoprotection, Tuberculose, Mycobactériose, Bactériose, Infection, Homme, Etude cas témoin
Mots-clés Pascal anglais : Vaccine, Epidemiology, BCG, Efficiency, Methodology, Brazil, South America, America, Immunoprotection, Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Human, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0280399
Code Inist : 002B30A01A1. Création : 199406.