Different roles for phenacetin and paracetamol in cancer of the kidney and renal pelvis.

Different roles for phenacetin and paracetamol in cancer of the kidney and renal pelvis.

Réf. 67472 Article - En anglais

INTERNATIONAL JOURNAL OF CANCER, vol. 53, n° 2, 1993, pages 245-249, 25 réf., ISSN 0020-7136, USA

MCCREDIE (M.) ^*, STEWART (J.H.), DAY (N.E.)

A population-based case-control study of kidney cancer was carried out in New South Wales using data from structured interviews with 489 cases of renal-cell cancer and 147 cases of renal pelvic cancer diagnosed in 1989 and 1990, together with 523 controls from the electoral rolls.
This study showed that the risk of renal pelvic cancer was increased by phenacetin/aspirin compound analgesics (RR=12.2; 95% CI 6.8-22.2) to a far greater extent than by paracetamol (RR=1.3; 95% CI 0.7-2.4; not significant).
There was a doubling of risk (RR=2.0; 95% CI 0.9-4.4) in the highest tertile of paracetamol taken in any form compared with values for non-users of any type of analgesic.

Mots-clés BDSP : Cancer, Facteur risque, Rein [pathologie], Appareil urinaire [pathologie], Australie, Océanie, Epidémiologie, Carcinogène, Médicament analgésique, Homme

Mots-clés Pascal : Tumeur maligne, Bassinet, Phénacétine, Paracétamol, Rein, Facteur risque, Rein pathologie, Appareil urinaire pathologie, Nouvelle Galles du Sud, Australie, Océanie, Epidémiologie, Carcinogène, Analgésique, Toxicité, Homme

Mots-clés Pascal anglais : Malignant tumor, Renal pelvis, Kidney, Risk factor, Renal disease, Urinary system disease, New South Wales, Australia, Oceania, Epidemiology, Carcinogen, Analgesic, Toxicity, Human

Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique

Cote : 93-0278949
Code Inist : 002B02U06. Création : 199406.

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