Development of multiple primary cutaneous melanomas is a well-recognized phenomenon.
As with single primary melanoma, personal and family histories of melanoma and dysplastic nevi (DN) are considered important risk factors.
The natural history and impact of regular follow-up evaluation of this entity were examined.
Through a search of the computerized data bank of the Pathology Department and the Melanoma Registry of the Pigmented Lesion Clinic at Massachusetts General Hospital, 41 patients with multiple cutaneous melanomas were identified.
Mean (+-standard error) age at first diagnosis was 49+-2 years (range, 21-75 years).
The male to female ratio was 2:1. The median number of primary melanomas was two (88%).
Mots-clés Pascal : Mélanome malin, Naevus dysplasique, Epidémiologie, Peau, Multiple, Tumeur maligne, Peau pathologie, Antécédent, Etude familiale, Massachusetts, Etats Unis, Amérique du Nord, Amérique, Homme
Mots-clés Pascal anglais : Malignant melanoma, Dysplastic nevus, Epidemiology, Skin, Multiple, Malignant tumor, Skin disease, Antecedent, Family study, Massachusetts, United States, North America, America, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0635052
Code Inist : 002B08A. Création : 199406.