Highly sensitive case definitions were first introduced by national poliomyelitis eradication programmes to avoid missing true cases of the disease, though false-positive diagnostic errors could still occur owing to low specificity.
Extensive data from all 1 620 cases of acute, flaccid paralysis reported in Brazil during 1987-88 provided an opportunity to study the characteristics of confirmed poliomyelitis cases and epidemiologically to evaluate potential case definitions that maximized both sensitivity and specificity.
Cases that had been confirmed by wild poliomyelitis virus isolation were compared with those that had been rejected (non-polio cases).
Mots-clés Pascal : Virose, Infection, Diagnostic, Homme, Etude cas, Exploration microbiologique, Poliomyélite, Eradication, Programme sanitaire, Confirmation, Essai laboratoire, Brésil, Amérique du Sud, Amérique
Mots-clés Pascal anglais : Viral disease, Infection, Diagnosis, Human, Case study, Microbiological investigation, Eradication, Sanitary program, Laboratory test, Brazil, South America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0363044
Code Inist : 002B30A. Création : 199406.