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  1. Is there etiologic heterogeneity between upper and lower neural tube defects ?

    Article - En anglais

    Neural tube defects are thought to arise from two different embryologic mechanisms depending on the level of the defect: neurulation defects associated with anencephaly and upper spina bifida and canalization defects associated with lower spina bifida.

    To investigate whether the risk profiles of neural tube defect cases differ according to the level of the defect, the authors examined data from the Atlanta Birth Defects Case-Control Study.

    Cases were infants liveor stillborn from 1968 to 1980 with these defects, and controls were infants without defects randomly selected and frequency matched to cases by race, birth year, and hospital of birth.

    Mots-clés Pascal : Anencéphalie, Spina bifida, Etiopathogénie, Localisation, Tube neural, Système nerveux pathologie, Encéphale pathologie, Maladie congénitale, Malformation, Nourrisson, Homme, Epidémiologie, Système ostéoarticulaire pathologie, Rachis pathologie, Facteur risque, Etude comparative, Système nerveux central pathologie, Géorgie, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin

    Mots-clés Pascal anglais : Anencephaly, Spina bifida, Etiopathogenesis, Localization, Neural tube, Nervous system diseases, Cerebral disorder, Congenital disease, Malformation, Infant, Human, Epidemiology, Diseases of the osteoarticular system, Disease of the spine, Risk factor, Comparative study, Georgia, United States, North America, America, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0284062

    Code Inist : 002B17D. Création : 199406.