Risk factors were studied in 96 children with congenital hydrocephalus (CH) coming from 118,265 consecutive births of known outcome.
Hydrocephalus with neural tube defects, intracranial tumors or secondary to brain atrophy were excluded.
The prevalence of CH was 0.81 per thousand.
Diagnosis was performed prenatally in 41 cases.
Forty-three (44.8%) of the cases had hydrocephalus without other malformations (isolated hydrocephalus), 18 (18.7%) infants hadrecognized chromosomal or non-chromosomal syndromes and 35 children (36.4%) had multiple malformations.
Each case was matched to a control.
Mots-clés Pascal : Malformation, Congénital, Système nerveux pathologie, Déterminisme génétique, Epidémiologie, Facteur risque, Homme, Enfant, Hydrocéphalie
Mots-clés Pascal anglais : Malformation, Congenital, Nervous system diseases, Inheritance, Epidemiology, Risk factor, Human, Child, Hydrocephaly
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0261434
Code Inist : 002B17D. Création : 199406.