Hereditary breast cancer in Sweden : a predominance of maternally inherited cases.
The family history of breast cancer was studied in 1975 breast cancer patients of all ages.
All the patients were found in an ongoing care program for breast cancer patients in the Stockholm area.
One hundred and thirty-three families (6.7%) with hereditary breast cancer, 87 (4,4%) families with hereditary breast- and other cancers, and 14 (0.7%) families with the SBLA syndrome were found.
There was no association betweenfamiliality and bilateral disease, but familial cases tended to be younger at the time of diagnosis.
Determination of the parental origin of the disease gene among the index cases revealed twice as many cases where the disease was maternally transmitted.
Mots-clés Pascal : Glande mammaire, Glande mammaire pathologie, Tumeur maligne, Maladie héréditaire, Homme, Origine maternelle, Origine paternelle, Etude familiale, Epidémiologie, Prévalence, Suède, Europe
Mots-clés Pascal anglais : Mammary gland, Mammary gland diseases, Malignant tumor, Genetic disease, Human, Maternal origin, Paternal origin, Family study, Epidemiology, Prevalence, Sweden, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0252882
Code Inist : 002B20E02. Création : 199406.