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  1. Familial aggregation of a disease consequent upon correlation between relatives in a risk factor measured on a continuous scale.

    Article - En anglais

    Correlation between relatives in one or more risk factors for a disease will contribute to the risk in relatives of an affected individual, irrespective of the cause(s) of the correlation.

    In this paper, a model is proposed to quantify the relation between 1) the correlation (p) between a random pair of relatives in a quantitative risk factor, 2) the dependence of the probability of being affected on a risk factor, assumed to be a logistic function and summarized by a risk ratio (RR) between upper and lower quartiles, and 3) the resultant disease association between relatives, represented as an odds ratio.

    Mots-clés Pascal : Modèle statistique, Etude familiale, Nutrition, Facteur risque, Analyse corrélation, Glande mammaire pathologie, Méthodologie, Epidémiologie, Tumeur maligne, Glande mammaire, Homme

    Mots-clés Pascal anglais : Statistical model, Family study, Nutrition, Risk factor, Correlation analysis, Mammary gland diseases, Methodology, Epidemiology, Malignant tumor, Mammary gland, Human

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    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0217394

    Code Inist : 002B30A01A1. Création : 199406.