To determine the incidence of persistent hepatitis B virus infection and its etiologic role as a cause of hepatoma, the authors carried out a case-control investigation of 70 persons with hepatoma, 70 controls, and their families in 1981-1982 in The Gambia, West Africa.
The risk of developing hepatoma after the age of 39 years was 1.4% in men and 0.3% in women.
Hepatoma occurred more than twice as frequently among persons who had four or more older siblings as among persons who had less than two older siblings.
Mots-clés Pascal : Hépatome, Hépatite virale B, Gambie, Afrique, Epidémiologie, Homme, Appareil digestif pathologie, Foie pathologie, Tumeur maligne, Chronique, Etude familiale, Virose, Infection, Age apparition, Incidence, Rang naissance, Etude cas témoin
Mots-clés Pascal anglais : Liver cell carcinoma, Gambia, Africa, Epidemiology, Human, Digestive diseases, Hepatic disease, Malignant tumor, Chronic, Family study, Viral disease, Infection, Age of onset, Incidence, Birth order, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0217392
Code Inist : 002B13C01. Création : 199406.