It is frequently assumed that the risk of hepatocellular carcinoma related to hepatitis B virus is higher when chronic hepatitis B virus infection is acquired early in life.
This hypothesis has never been directly evaluated.
However, firstborn and secondborn children are exposed to common infections after their school enrollment, whereas later-born children are exposed much earlier, through their older siblings.
The authors analyzed sibship size and birth order data from a large case-control study of patients admitted to Athens, Greece, hospitals between April 1976 and October 1984.
Mots-clés Pascal : Epithélioma, Epidémiologie, Hépatite virale B, Foie, Tumeur maligne, Age apparition, Rang naissance, Chronique, Appareil digestif pathologie, Foie pathologie, Virose, Infection, Enfant, Homme, Grèce, Europe, Etude cas témoin
Mots-clés Pascal anglais : Carcinoma, Epidemiology, Liver, Malignant tumor, Age of onset, Birth order, Chronic, Digestive diseases, Hepatic disease, Viral disease, Infection, Child, Human, Greece, Europe, Case control study
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 93-0217391
Code Inist : 002B13C01. Création : 199406.