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  1. Control-informant agreement on exposure history in case-control studies of Alzheimer's disease.

    Article - En anglais

    Data on control-informant agreement from four published case-control studies of Alzheimer's disease are compared, using both the kappa statistic and proportion of agreement for the presence and absence of exposures.

    Agreement was best for exposures involving lifestyle, medical interventions or disorders of more recent origin, and worst for exposures which involved judgements by the respondent.

    Agreement levels are similar across studies, and are commensurate with levels of specificity and sensitivity to be expected in this type of enquiry.

    We discuss the problems and implications associated with the interpretation of data from such studies of the elderly.

    Mots-clés Pascal : Epidémiologie, Exposition professionnelle, Démence Alzheimer, Collecte donnée, Histoire, Biais méthodologique, Méthodologie, Rappel, Mémoire, Système nerveux pathologie, Encéphale pathologie, Maladie dégénérative, Système nerveux central pathologie, Informateur, Fiabilité, Analyse statistique, Homme, Etude cas témoin

    Mots-clés Pascal anglais : Epidemiology, Occupational exposure, Alzheimer disease, Data gathering, History, Methodological bias, Methodology, Recall, Memory, Nervous system diseases, Cerebral disorder, Degenerative disease, Reliability, Statistical analysis, Human, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 93-0202733

    Code Inist : 002B30A01A1. Création : 199406.